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Stefan Mihalas

Investigator, D3 Scientific

teams /
Allenite

Stefan Mihalas joined the Allen Institute in 2011 from Johns Hopkins University, where he was a postdoctoral fellow in neuroscience and subsequently an associate research scientist. As a computational neuroscientist, Mihalas has worked on models of both molecular and systems neuroscience including nervous system development, synaptic plasticity, minimalistic spiking neuron models, self-organized criticality, visual attention and figure ground segregation. His current research interests are aimed at building models to elucidate how large networks of interacting neurons produce cognitive behaviors. At the Allen Institute, Mihalas integrates anatomical and physiological connectivity data to generate models of visual perception in the mouse. To this end, he works to build a series of models of increasing complexity for both individual components, i.e., neurons, synapses, and microcircuits, as well as for large portions of the entire system. This series of models will be compared to the simplified theoretical predictions from statistical physics, information theory and computer vision. Mihalas received his Diploma in physics and M.S. in mathematics from West University of Timisoara in Romania. He received his Ph.D. in physics from the California Institute of Technology.

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publication / 2025
Integrating multimodal data to understand cortical circuit architecture and function
Nature Neuroscience
publication / 2024
Simple synaptic modulations implement diverse novelty computations
Cell Reports
publication / 2024
Backward masking in mice requires visual cortex
Nature Neuroscience

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