Stephanie Seeman
Scientist III
Stephanie joined the Allen Institute for Brain Science in 2016 and has contributed to multiple large-scale efforts including the Synaptic Physiology Pipeline and spatial transcriptomic atlasing of mammalian brains. Stephanie earned her Ph.D. in Neuroscience from the University of Washington, where she worked with Dr. Steve Perlmutter and Dr. Eberhard Fetz to understand the connectivity and plasticity of sensorimotor cortex using in vivo recordings of population local field potentials. Prior to that, she researched synaptic processing in the auditory brainstem using in vitro electrophysiological methods under Dr. Nace Golding at the University of Texas, Austin. Stephanie earned her B.S. in Biology from Union College in Schenectady, NY.
research focus
The complex processing of the brain is intimately tied to the structural and functional organization that individual neurons and networks of neurons possess. I am broadly interested in understanding brain architecture and function using multiple techniques. With the multi-patch team, I recorded from many neurons simultaneously to uncover the transmission of neural signals between them, using transgenic mouse lines to describe the connections of specific neuron types. More recently, I have been utilizing Spatial Transcriptomics to map gene expression across brain tissue, enabling a deeper understanding of cell types and their organization in space. Together, these approaches contribute to a more comprehensive view of brain structure and function.
