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This first release includes electrical properties from approximately 300 living cortical neurons of different types derived from 36 patients, with accompanying 3D reconstructions of their shape or anatomy for 100 cells, and computer models simulating the electrical behavior of these neurons.
The database will also contain gene expression profiles, based on measurements of all genes used by 16,000 individual cells, from three adult human brains. Data from these human cells provide an unparalleled window into the intricate components, circuitry and function of the human neocortex, including features that make our brains unique.
The Allen Cell Types Database is freely available at http://celltypes.brain-map.org.
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The Allen Institute is an independent, 501(c)(3) nonprofit research organization founded by philanthropist and visionary, the late Paul G. Allen. The Allen Institute is dedicated to answering some of the biggest questions in bioscience and accelerating research worldwide. The Institute is a recognized leader in large-scale research with a commitment to an open science model. For more information, visit alleninstitute.org.