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From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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Zapping the right brain cells: The path to improved stimulation

New findings could help scientists develop better ways to treat brain disorders with electrical stimulation.
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Scientists create ChatGPT-like AI model for neuroscience to build detailed mouse brain map
Scientists create ChatGPT-like AI model for neuroscience to build one of the most detailed mouse brain maps to date.
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New study reveals rheumatoid arthritis begins long before symptoms, opening door to prevention
The seven-year study reveals early-warning signs that could help doctors catch the disease before it starts, potentially saving patients years of pain and disability.
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Simularium: Accelerating discovery by animating insight
Simularium is an innovative online tool designed by the Allen Institute’s Cell Science team that visualizes 4D simulations (animations) of complex...
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Scientists use Open Ephys GUI to study how psychedelics affect the brain
Software co-created by the Allen Institute is helping scientists better understand psilocybin, which could lead to new treatments for neuropsychiatric disorders like depression
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What is open science
How sharing knowledge accelerates innovation and advances discovery
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Scientists shoot lasers into brain cells to uncover how illusions work
Supported by the Allen Institute's OpenScope program, the findings could help us better understand neuropsychiatric disorders like schizophrenia and...
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Allen Institute cells blast off into outer space
Researchers from Cedars-Sinai are using Allen Institute cell lines to grow organoids in space, which could help design better drugs for disease
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Unlocking discovery
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Learning how to learn with brains, data and optimization
A Shanahan Fellow’s experience to uncover how the brain multitasks and adapts to the world around it.
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First-ever Open Science Quest supports the next generation of scientists
The course offered career and technical education credits that counted for high school graduation and helped prepare students for the realities of...
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What Are the Parts of a Cell?
From mitochondria to endoplasmic reticulum, this educational video explores the major cell organelles and their functions.
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Before the breakthrough: Why basic science matters
A look at how the Allen Institute uses basic science to drive discovery and future breakthroughs.
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media / Axios
Axios: Scientists get a new tool to study a common genetic heart condition
Disease-specific cells developed by the Allen Institute for Cell Science offer a new window into the world's most common genetic heart condition.
media / Fierce Biotech
Fierce Biotech: Allen Institute's cell lines could lead to new drugs for hypertrophic cardiomyopathy
(Photo credit: Fierce Biotech) By helping scientists make generalizations about the disease by unearthing the common denominator between mutations, the cells could ultimately lead to more personalized treatment approaches.
media / GeekWire
GeekWire: Allen Institute and Seattle Children’s to study inflammatory bowel disorder in search of cure
media / Technology Networks
Technology Networks: BARSeq Reveals the Brain Is Like a Pointillism Painting
(Photo credit: Technology Networks/iStock) BARseq reveals that peripheral inputs can alter the identity of cortical neurons during development.
media / MyNorthwest / KIRO Radio
KIRO Radio: Breakthroughs in Synthetic Biology
(Interview starts 11:35 in) Troy McDiarmid from the Seattle Center for Synthetic Biology describes the innovative research underway to create cellular recorders that will track the full life histories of human cells to better understand disease.
media / Puget Sound Business Journal
Puget Sound Business Journal: Seattle biotech research hub launches with big goals for growth, scientific advances
The Seattle Hub for Synthetic Biology is developing technology to monitor genomic changes in cells in real time, in turn showing cells' whole histories and the genetic causes of disease.
media / Inside Precision Medicine
Inside Precision Medicine: How Single-Cell Omics is Revolutionizing Our View Of Neurobiology
(Photo credit: miakievy / Getty Images) The adult human brain is made up of billions of neurons and glial cells. Understanding the diversity of these cells and their distinctive gene-regulatory mechanisms is crucial for determining how the brain works and, in turn, for developing treatments for neurologic disorders
media / GeekWire
GeekWire: Inside the new Seattle Hub for Synthetic Biology, which uses DNA to ‘record biology over time’
(Photo credit: Charlotte Schubert) Researchers opened the doors Monday to the new Seattle Hub for Synthetic Biology, a collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington.
media / The Scientist
The Scientist: A Cell-by-Cell Map of the Entire Mouse Brain
This comprehensive map laid the foundation for the next stage of investigations, such as scaling up efforts to chart nonhuman primates and human brains.
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