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news from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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Zapping the right brain cells: The path to improved stimulation

New findings could help scientists develop better ways to treat brain disorders with electrical stimulation.
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news 
Tiny high-tech probes reveal how information flows across the brain
In the largest study of its kind to date, scientists use ‘Neuropixels’ probes to capture details of how the mouse brain sees the world
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3 immune mysteries of COVID-19 - and 1 big success story
The pandemic has revealed how much we really don’t know about our own immune systems, experts say
immunology
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Science in Sixty | Kathy Richmond
Kathryn Richmond, Senior Director of The Paul G. Allen Frontiers Group, is looking for the best ideas out there to change how we think about biology...
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Allen Institute President and Chief Executive Officer, Allan Jones, Ph.D., announces plan to step down in 2021
Today the Allen Institute’s founding CEO, Allan Jones, Ph.D., announced he will step down after nearly 18 years with the organization.
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New study aims to answer pressing COVID-19 question: Why do some die while others don’t even know they are sick?
Seattle-area research organizations team up for a deep dive into patients’ immune responses to the novel coronavirus; results could contribute to...
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These visual neurons catch what we might miss
When mice see faint objects approaching head on, certain neurons kick into gear - possibly to warn them
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Allen Institute for Cell Science announces leadership changes
Ruwanthi (Ru) Gunawardane, Ph.D., has been named Executive Director.
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Allen Institute announces 2020 Next Generation Leaders
Six early-career neuroscientists will participate in unique advisory council for the Institute
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The mammalian brain is built from many kinds of neurons. A new study reveals a holistic way to look at them.
Using a technique that simultaneously captures different kinds of features from each cell, researchers lay groundwork for a “family tree” of the brain.
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Mouse study uncovers links between unsung brain cells and Huntington’s disease - and possible path for human therapies
Astrocytes, once thought of as inert ‘brain glue,’ may turn out to be key players in Huntington’s and other neurodegenerative diseases
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New cell line lets researchers use CRISPR to reversibly switch off genes
‘CRISPR interference’ technique enables study of basic cell biology and disease in human stem cells
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2 scientists win Nobel chemistry prize for gene-editing tool
Allen Distinguished Investigator Jennifer A. Doudna and her colleague Emmanuelle Charpentier won for developing CRISPR-cas9, a very simple technique for cutting a gene at a specific spot.
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media / Wall Street Journal
The Quest to Decode the Brain
The Wall Street Journal - Thinking, moving, seeing—it all seems so easy.
media / Allen Institute
Diversity of Cortical Neurons Captured in Comprehensive Computer Models
The Allen Institute for Brain Science has produced the first comprehensive, publicly available database of predictive neuron models, along with their corresponding data.
media / Puget Sound Business Journal
PSBJ Innovator of the Year: Hacking cells at the Allen Institute
Puget Sound Business Journal - Paul Allen’s open-source research organization gives a head start to scientists fighting disease across the globe
media / Allen Institute
Researchers reveal new details on aged brain, Alzheimer's and dementia
In a comprehensive analysis of samples from 107 aged human brains, researchers at the Allen Institute for Brain Science, UW Medicine and Kaiser Permanente Washington Health Research Institute have discovered details that will help researchers better understand the biological bases for Alzheimer’s disease and dementia in older populations.
media / Allen Institute
Allen Institute for Brain Science announces 2017 Next Generation Leaders
The Allen Institute for Brain Science announces the newest cohort of Next Generation Leaders: a group of six distinguished early-career researchers who will provide feedback in both formal and informal settings to scientists at the Allen Institute.
media / Wall Street Journal
To Keep Up With AI, We’ll Need High-Tech Brains
The Wall Street Journal - When do we start panicking? DeepMind, an artificial intelligence company in London, just announced another breakthrough in machine intelligence.
media / GeekWire
Annotated guide to the brain: The Allen Institute creates 3-D map of mouse cortex
GeekWire - After years of painstaking work, Seattle’s Allen Institute for Brain Science has completed a digital 3-D map of the mouse cortex
media / The Economist
The first data from a repository of living human brain cells
The Economist - Waste not, want not
media / Wired
These Neurons are Alive and Firing. And You Can Watch Them In 3-D
Nature - Researchers are keeping little bits of brain tissue on life support long enough to dye, sequence, zap, and map out individual neurons in 3-D.
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