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From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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Zapping the right brain cells: The path to improved stimulation

New findings could help scientists develop better ways to treat brain disorders with electrical stimulation.
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news 
Tiny high-tech probes reveal how information flows across the brain
In the largest study of its kind to date, scientists use ‘Neuropixels’ probes to capture details of how the mouse brain sees the world
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3 immune mysteries of COVID-19 - and 1 big success story
The pandemic has revealed how much we really don’t know about our own immune systems, experts say
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Science in Sixty | Kathy Richmond
Kathryn Richmond, Senior Director of The Paul G. Allen Frontiers Group, is looking for the best ideas out there to change how we think about biology...
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Allen Institute President and Chief Executive Officer, Allan Jones, Ph.D., announces plan to step down in 2021
Today the Allen Institute’s founding CEO, Allan Jones, Ph.D., announced he will step down after nearly 18 years with the organization.
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New study aims to answer pressing COVID-19 question: Why do some die while others don’t even know they are sick?
Seattle-area research organizations team up for a deep dive into patients’ immune responses to the novel coronavirus; results could contribute to...
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These visual neurons catch what we might miss
When mice see faint objects approaching head on, certain neurons kick into gear - possibly to warn them
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Allen Institute for Cell Science announces leadership changes
Ruwanthi (Ru) Gunawardane, Ph.D., has been named Executive Director.
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Allen Institute announces 2020 Next Generation Leaders
Six early-career neuroscientists will participate in unique advisory council for the Institute
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The mammalian brain is built from many kinds of neurons. A new study reveals a holistic way to look at them.
Using a technique that simultaneously captures different kinds of features from each cell, researchers lay groundwork for a “family tree” of the brain.
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Mouse study uncovers links between unsung brain cells and Huntington’s disease - and possible path for human therapies
Astrocytes, once thought of as inert ‘brain glue,’ may turn out to be key players in Huntington’s and other neurodegenerative diseases
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New cell line lets researchers use CRISPR to reversibly switch off genes
‘CRISPR interference’ technique enables study of basic cell biology and disease in human stem cells
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2 scientists win Nobel chemistry prize for gene-editing tool
Allen Distinguished Investigator Jennifer A. Doudna and her colleague Emmanuelle Charpentier won for developing CRISPR-cas9, a very simple technique for cutting a gene at a specific spot.
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media / STAT News
A new window into the human brain
STAT - At one time or another, haven’t we all wanted to peer into the inner workings of someone else's brain?
media / Science
Fresh human brains yield delicious data
Science - Allen Institute for Brain Science launches first database of live human brain cells
media / NPR
Scientists And Surgeons Team Up To Create Virtual Human Brain Cells
NPR - Scientists in Seattle have created three-dimensional computer reconstructions of living human brain cells by studying tissue that is usually discarded during surgery.
media / Nature
Researchers add live human cells to brain database
Nature - Fresh human brain tissue is a vanishingly rare resource for neuroscientists.
media / GeekWire
They’re alive! Allen Institute harvests data from bits of living human brain tissue
GeekWire - Zapping brain cells from living human tissue? It sounds like a creepy Halloween tale.
media / Forbes
Paul Allen Just Made His Biggest Step Yet To Map The Human Brain
Forbes - When the Allen Institute for Brain Science launched its Cell Types Database just over two years ago, its goal was to help create a comprehensive map of the human brain
media / Allen Institute
Allen Institute shares first open database of live human brain cells
Brain samples from neurosurgery patients reveal uniqueness and complexity of the human brain
media / Allen Institute
Allen Institute for Brain Science awarded ~$100 million to lead global collaborations that will build comprehensive atlases of brain cell types
National Institutes of Health funding expands work to identify and catalog the building blocks of the brain, and creates global center for data sharing
media / GeekWire
Brain scientist Christof Koch maps out a path to merge humans and machines
GeekWire - It may sound like a zombie movie, but Seattle’s Allen Institute for Brain Science is studying fresh human brain tissue to see up close how our neurons work.
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