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From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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Zapping the right brain cells: The path to improved stimulation

New findings could help scientists develop better ways to treat brain disorders with electrical stimulation.
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Tiny high-tech probes reveal how information flows across the brain
In the largest study of its kind to date, scientists use ‘Neuropixels’ probes to capture details of how the mouse brain sees the world
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3 immune mysteries of COVID-19 - and 1 big success story
The pandemic has revealed how much we really don’t know about our own immune systems, experts say
immunology
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Science in Sixty | Kathy Richmond
Kathryn Richmond, Senior Director of The Paul G. Allen Frontiers Group, is looking for the best ideas out there to change how we think about biology...
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Allen Institute President and Chief Executive Officer, Allan Jones, Ph.D., announces plan to step down in 2021
Today the Allen Institute’s founding CEO, Allan Jones, Ph.D., announced he will step down after nearly 18 years with the organization.
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New study aims to answer pressing COVID-19 question: Why do some die while others don’t even know they are sick?
Seattle-area research organizations team up for a deep dive into patients’ immune responses to the novel coronavirus; results could contribute to...
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These visual neurons catch what we might miss
When mice see faint objects approaching head on, certain neurons kick into gear - possibly to warn them
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Allen Institute for Cell Science announces leadership changes
Ruwanthi (Ru) Gunawardane, Ph.D., has been named Executive Director.
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Allen Institute announces 2020 Next Generation Leaders
Six early-career neuroscientists will participate in unique advisory council for the Institute
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The mammalian brain is built from many kinds of neurons. A new study reveals a holistic way to look at them.
Using a technique that simultaneously captures different kinds of features from each cell, researchers lay groundwork for a “family tree” of the brain.
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Mouse study uncovers links between unsung brain cells and Huntington’s disease - and possible path for human therapies
Astrocytes, once thought of as inert ‘brain glue,’ may turn out to be key players in Huntington’s and other neurodegenerative diseases
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New cell line lets researchers use CRISPR to reversibly switch off genes
‘CRISPR interference’ technique enables study of basic cell biology and disease in human stem cells
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2 scientists win Nobel chemistry prize for gene-editing tool
Allen Distinguished Investigator Jennifer A. Doudna and her colleague Emmanuelle Charpentier won for developing CRISPR-cas9, a very simple technique for cutting a gene at a specific spot.
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media / Nautilus
The Spiritual, Reductionist Consciousness of Christof Koch
Nautilus - Consciousness is a thriving industry. It’s not just the meditation retreats and ayahuasca shamans.
media / The Verge
Lab-made tadpole cyclopes could help with human organ transplants
The Verge - At first blush, a blind tadpole that’s had an eyeball grafted onto its tail sounds like a creature from a fairy tale.
media / New Scientist
Tadpoles learn to see with new eyes transplanted on their tails
New Scientist - Blind tadpoles have learned to see again, using eyes implanted on their tails.
media / Fierce Biotech
Migraine drug activates transplanted eyes in tadpoles
Fierce Biotech - What can blind tadpoles teach us about improving organ transplants, correcting birth defects and curing cancer?
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media / Seeker
This Giant Neuron Could Explain Where Consciousness Comes From
Seeker - After uncovering three giant neurons, scientists could be one step closer to pinpointing where consciousness lives in the brain.
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media / The Conversation
How mapping teenagers’ brains has helped us understand more about schizophrenia
The Conversation - When I was studying for my PhD at the University of California at Berkeley, I spent an awful lot of my weekends asking teenagers to lie still in a magnetic resonance imaging (MRI) scanner.
media / Nature
A giant neuron found wrapped around entire mouse brain
Nature - 3D reconstructions show a 'crown of thorns' shape stemming from a region linked to consciousness.
media / Engineering News-Record
Best of the Best 2016: Higher Education/Research: Allen Institute
Engineering News-Record - The facility, which houses the Allen Institute for Brain Science, the Allen Institute for Cell Science and Paul G. Allen Frontiers, is located just south of Lake Union.
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media / Quartz
The discovery of a giant neuron could help explain how the brain creates consciousness
Quartz - Nobody yet understands how a collection of mushy cells in the brain gives rise to the brilliance of consciousness seen in higher-order animals, including humans.
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