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news from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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Zapping the right brain cells: The path to improved stimulation

New findings could help scientists develop better ways to treat brain disorders with electrical stimulation.
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video 
Where does Alzheimer's begin?
Pinpointing the cellular roots of Alzheimer's disease to find new targets for treatments and therapies.
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Cell by cell, scientists are building a high-resolution map of brain changes in Alzheimer’s disease
A massive dataset of 1.2M brain cells shines a light on disease’s cellular roots
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DNA Typewriter keeps a record of cells’ long histories
Molecular recording device could be used to trace cell-by-cell growth of an entire animal
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SciShots: The 3D network inside a mouse’s brain
Scientists are piecing together the puzzle of the brain using light-sheet microscopy
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SciShots: Brain tumors in high-res
Scientists are using tumor “spheroids” to study glioblastoma, a deadly brain cancer
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SciShots: Exploring cellular variability
Scientists are studying the wide range of “normal” within human cells
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Out of Balance | Sarah’s experience with multiple myeloma
Sarah Kaufmann-Fink was diagnosed with cancer as a college student. 17 years and one relapse later, she’s pushing for more research.
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Science in Sixty | Greg Szeto
Greg Szeto Ph.D., Associate Investigator at The Allen Institute for Immunology, has a passion for immunology, virology, bioengineering, computer science…and photographing live music! Check out our latest Science In Sixty feature.
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A new open-access portal for human immunology data and tools
The Human Immune System Explorer offers an inside view into ongoing research on human health and disease
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SciShots: Glowing muscles of the comb jelly
Biologists are studying the neurons and muscle cells of the ctenophore, a type of sea jelly that is the sister group to all other animals
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Science in Sixty | Irina Mueller
A recipe for success - Scientific Program Manager, Irina Mueller, supports interdisciplinary teams working together to understand the human cell.
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SciShots: A quartet of brain cells
Scientists are sifting through the hundreds of thousands of brain cells present in a cubic millimeter of mouse brain
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media / Axios
Axios: Scientists get a new tool to study a common genetic heart condition
Disease-specific cells developed by the Allen Institute for Cell Science offer a new window into the world's most common genetic heart condition.
media / Fierce Biotech
Fierce Biotech: Allen Institute's cell lines could lead to new drugs for hypertrophic cardiomyopathy
(Photo credit: Fierce Biotech) By helping scientists make generalizations about the disease by unearthing the common denominator between mutations, the cells could ultimately lead to more personalized treatment approaches.
media / GeekWire
GeekWire: Allen Institute and Seattle Children’s to study inflammatory bowel disorder in search of cure
media / Technology Networks
Technology Networks: BARSeq Reveals the Brain Is Like a Pointillism Painting
(Photo credit: Technology Networks/iStock) BARseq reveals that peripheral inputs can alter the identity of cortical neurons during development.
media / MyNorthwest / KIRO Radio
KIRO Radio: Breakthroughs in Synthetic Biology
(Interview starts 11:35 in) Troy McDiarmid from the Seattle Center for Synthetic Biology describes the innovative research underway to create cellular recorders that will track the full life histories of human cells to better understand disease.
media / Puget Sound Business Journal
Puget Sound Business Journal: Seattle biotech research hub launches with big goals for growth, scientific advances
The Seattle Hub for Synthetic Biology is developing technology to monitor genomic changes in cells in real time, in turn showing cells' whole histories and the genetic causes of disease.
media / Inside Precision Medicine
Inside Precision Medicine: How Single-Cell Omics is Revolutionizing Our View Of Neurobiology
(Photo credit: miakievy / Getty Images) The adult human brain is made up of billions of neurons and glial cells. Understanding the diversity of these cells and their distinctive gene-regulatory mechanisms is crucial for determining how the brain works and, in turn, for developing treatments for neurologic disorders
media / GeekWire
GeekWire: Inside the new Seattle Hub for Synthetic Biology, which uses DNA to ‘record biology over time’
(Photo credit: Charlotte Schubert) Researchers opened the doors Monday to the new Seattle Hub for Synthetic Biology, a collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington.
media / The Scientist
The Scientist: A Cell-by-Cell Map of the Entire Mouse Brain
This comprehensive map laid the foundation for the next stage of investigations, such as scaling up efforts to chart nonhuman primates and human brains.
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