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From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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Zapping the right brain cells: The path to improved stimulation

New findings could help scientists develop better ways to treat brain disorders with electrical stimulation.
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science images
SciShots: The Brain’s Cleanup Crew and Paramedics
The shape-shifting microglia play a vital role in maintaining brain health
brain science
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Mapping the whole human brain: Allen Institute to lead global collaboration
NIH BRAIN Initiative to fund primate brain atlases, maps of developing mouse brain, coordination and knowledge sharing, and brain function research
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SciShots: The brain’s mysterious, multipurpose immune system
Microglial cells act as the brain’s waste disposal when healthy - can they be manipulated to protect against disease?
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Opening up about open science
In five words, more or less, what does open science mean to you? We asked our talented teams at the Allen Institute who work on openly available...
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Look in the labs | Electron Microscopy Suite
See how researchers at the Allen Institute are using electron microscopy to map intricate connections between brain cells at ultra-high resolution.
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Look in the labs | Immunology
What makes the human immune system healthy, and what goes wrong in disease?
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Look in the labs | Neural Dynamics
How do different brain regions connect and communicate? Researchers at the Allen Institute for Neural Dynamics are 3D imaging whole mouse brains in...
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Look in the labs | Cell Science
Cells are the building blocks of life.
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23 interns, 4 coffee machines, 1 summer: Through the eyes of this year’s cohort of budding science professionals
Allen Institute welcomes interns on-site for the first time since 2019 - these are some of their stories
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From 300,000 mouse neurons, scientists hope to glean how the brain drives behavior
New public dataset captures billions of electrical spikes from brains of animals trained to identify ‘oddball’ photos
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A prescription for exercise: Scientists want to help you find the best workout for your brain
Researchers are developing a fitness wearable to personalize exercise and lower the risks of dementia
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SciShots: Clusters of Alzheimer’s cells
New data explores the cellular landscape of Alzheimer’s disease
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media / Forbes
Biologists Get $100 Million From Billionaire Paul Allen To Investigate Cells
With a gift of $100 million from billionaire philanthropist Paul G. Allen, scientists will embark on an effort to understand how cells work and how they malfunction in disease. Leaders of this new endeavor announced the launch of the Seattle-based Allen Institute for Cell Science today at the annual meeting of the American Society for Cell Biology in Philadelphia.
media / Nature
Microsoft billionaire takes on cell biology
Billionaire businessman and philanthropist Paul Allen plans to pump US$100 million into investigating the most basic unit of life — the cell.
media / Scientific American
Billionaire's New Science Institute Plans "Google Maps" View of Cells
We have not been seeing cells as they really are, says Rick Horwitz, and it is time for that to change.
media / Washington Post
Billionaire Paul Allen donates $100m to new ‘industrial scale’ effort to understand human cells
Microsoft co-founder Paul G. Allen is donating $100 million of his fortune to launch what he calls an “industrial-scale” effort to understand the basic building block of all living things: the cell.
media / Seattle Times
Allen gives $100 million for new Seattle institute to unravel cells
Paul Allen’s new cell-science institute will share more than a building with the brain-research center the Microsoft mogul established in his hometown 11 years ago.
media / GeekWire
Paul Allen gives $100M to create new Allen Institute for Cell Science
Paul Allen is again dolling out a huge chunk of money to fuel scientific research.
media / Science
Microsoft mogul to create new cell science center
Science - Eleven years after he established an institute dedicated to mapping the brain, Microsoft co-founder Paul Allen is announcing a sequel: the Allen Institute for Cell Science. Just like its predecessor, the new institute will be seeded with $100 million from Allen himself; will embrace big-team science, bringing together cell biologists, mathematicians, computational biologists, and other specialists; and will seek to decipher a world whose complexity is still largely uncharted.
media / Discover Magazine
Building the Mouse Brain Mega Map
Discover Magazine - Scientists imaged more than 1,700 mouse brains to build the most comprehensive mammalian brain map yet.
media / NPR
A Genetic Map Hints At What Makes A Brain Human
NPR - Patterns of gene expression in human and mouse brains suggest that cells known as glial cells may have helped us evolve brains that can acquire language and solve complex problems.
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