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From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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Zapping the right brain cells: The path to improved stimulation

New findings could help scientists develop better ways to treat brain disorders with electrical stimulation.
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news 
Advancing Leading Edge Cancer Research in a $4.5 Million Collaboration
LLS, The Mark Foundation for Cancer Research and The Paul G. Allen Frontiers Group Join Forces to Advance Leading Edge Cancer Research
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Sorting neurons by their shape and activity to understand the elements making up the brain
To understand our brains, scientists need to know their components. This theme underlies a growing effort in neuroscience to define the different building blocks of the brain — its cells.
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A model for how the brain stays in sync
In the brain, connections are key. A mouse brain contains around a billion synapses, or physical connections between neurons, and our own brains house approximately 100 trillion.
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Allen Institute for Cell Science Debuts First Comprehensive View of Human Cell Division
The data-driven model sheds new light on mitosis, a critical process for human cells and a pivotal driver of cancer
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Out of Balance | Alyssa’s life with Crohn’s disease
Ever since Alyssa Clements can remember, she’s wanted to be a doctor. Her father is a chiropractor in south New Jersey, and his business partner was...
immunology
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New Cell Registry enables exploration of multiple brain cell type datasets
The Allen Institute for Brain Science, a division of the Allen Institute, has debuted a new data exploration tool for brain cell type data.
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How do living creatures take shape?
Think of the shape of life. Living creatures have forms ranging from a tiny rod-shaped bacterium, to a wrinkled, tusked behemoth of an elephant, to a...
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Q&A: A former experimental psychologist with a passion for data governance
Scientists everywhere are struggling with data. Paul Meijer, Ph.D., Director of Software Development at the newly launched Allen Institute for...
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Gene drives get a precision upgrade
Gene drives, a method to “drive” a new gene through a population in a way that bypasses the natural order of inheritance, were first developed...
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A new technique to make beating human heart cells glow
Allen Institute for Cell Science researchers have developed a new technique that will enable better understanding of human heart muscle cells.
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Data Stories | Addiction & the visual system
Researcher Randy Ellis studies computational neuroscience and addiction. Ellis uses the Allen Brain Observatory dataset in his work to find new ways...
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How immune cells detect different threat levels from salmonella
Your immune system has a tough job.
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media / Axios
Axios: Scientists get a new tool to study a common genetic heart condition
Disease-specific cells developed by the Allen Institute for Cell Science offer a new window into the world's most common genetic heart condition.
media / Fierce Biotech
Fierce Biotech: Allen Institute's cell lines could lead to new drugs for hypertrophic cardiomyopathy
(Photo credit: Fierce Biotech) By helping scientists make generalizations about the disease by unearthing the common denominator between mutations, the cells could ultimately lead to more personalized treatment approaches.
media / GeekWire
GeekWire: Allen Institute and Seattle Children’s to study inflammatory bowel disorder in search of cure
media / Technology Networks
Technology Networks: BARSeq Reveals the Brain Is Like a Pointillism Painting
(Photo credit: Technology Networks/iStock) BARseq reveals that peripheral inputs can alter the identity of cortical neurons during development.
media / MyNorthwest / KIRO Radio
KIRO Radio: Breakthroughs in Synthetic Biology
(Interview starts 11:35 in) Troy McDiarmid from the Seattle Center for Synthetic Biology describes the innovative research underway to create cellular recorders that will track the full life histories of human cells to better understand disease.
media / Puget Sound Business Journal
Puget Sound Business Journal: Seattle biotech research hub launches with big goals for growth, scientific advances
The Seattle Hub for Synthetic Biology is developing technology to monitor genomic changes in cells in real time, in turn showing cells' whole histories and the genetic causes of disease.
media / Inside Precision Medicine
Inside Precision Medicine: How Single-Cell Omics is Revolutionizing Our View Of Neurobiology
(Photo credit: miakievy / Getty Images) The adult human brain is made up of billions of neurons and glial cells. Understanding the diversity of these cells and their distinctive gene-regulatory mechanisms is crucial for determining how the brain works and, in turn, for developing treatments for neurologic disorders
media / GeekWire
GeekWire: Inside the new Seattle Hub for Synthetic Biology, which uses DNA to ‘record biology over time’
(Photo credit: Charlotte Schubert) Researchers opened the doors Monday to the new Seattle Hub for Synthetic Biology, a collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington.
media / The Scientist
The Scientist: A Cell-by-Cell Map of the Entire Mouse Brain
This comprehensive map laid the foundation for the next stage of investigations, such as scaling up efforts to chart nonhuman primates and human brains.
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