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From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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Zapping the right brain cells: The path to improved stimulation

New findings could help scientists develop better ways to treat brain disorders with electrical stimulation.
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Hongkui Zeng, Ph.D., Executive Vice President, Director of the Allen Institute for Brain Science, elected to National Academy of Medicine
Election to the Academy is considered one of the highest honors in the fields of health and medicine and recognizes leaders who have demonstrated...
brain science
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Projects launch to map brain connections in mouse and macaque
NIH BRAIN Initiative-funded research will lay the groundwork to map entire brains in incredible detail
brain science
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Seattle Mayor Bruce Harrell and Executive of King County, Dow Constantine, declare Saturday, September 16 "Open Science Day"
This honor marks Allen Institute's 20th Anniversary
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SciShots: A tree-like mouse lung
Scientists are learning the bartering system of two cell types to understand the lifecycle of a lung
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Brain expansion brings bigger brains and clearer images, with the help of a diaper chemical
Clear, jelly-like mouse brains are the new gamechangers in neuroscience
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Allen Institute for Immunology partners with Lilly to better understand autoimmune disease
The Institute will use cutting-edge molecular profiling techniques and advanced bioinformatics tools to enable precision medicine in clinical trials...
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Scientific Overview | ExA-SPIM
A high-level explanation of the protocols necessary to implement the Expansion Selective Plane Illumination Microscopy (ExA–SPIM) pipeline
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New OpenScope projects aim to shed light on how we process our visual world
OpenScope is a shared neuroscience platform modeled after astronomy’s shared observatories
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Ananda Goldrath to Lead Allen Institute for Immunology
Dr. Ananda Goldrath will join as the Executive Vice President of the Allen Institute for Immunology in fall of 2023.
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Andy Hickl joins Allen Institute as Chief Technology Officer
Throughout his career, Hickl has led teams that used natural language processing, machine learning, artificial intelligence, and computer vision to tackle some of the world’s most important problems—from climate change and clean energy to biodiversity and global health.
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Long COVID’s long fallout
Patients share their experiences of ongoing, debilitating symptoms nearly 3 years after initial infection
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A new, custom-built microscope is capturing stunning views of the brain
‘ExA-SPIM’ microscope borrows from electronics industry to image incredible detail in an entire mouse brain
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media / Axios
Axios: Scientists get a new tool to study a common genetic heart condition
Disease-specific cells developed by the Allen Institute for Cell Science offer a new window into the world's most common genetic heart condition.
media / Fierce Biotech
Fierce Biotech: Allen Institute's cell lines could lead to new drugs for hypertrophic cardiomyopathy
(Photo credit: Fierce Biotech) By helping scientists make generalizations about the disease by unearthing the common denominator between mutations, the cells could ultimately lead to more personalized treatment approaches.
media / GeekWire
GeekWire: Allen Institute and Seattle Children’s to study inflammatory bowel disorder in search of cure
media / Technology Networks
Technology Networks: BARSeq Reveals the Brain Is Like a Pointillism Painting
(Photo credit: Technology Networks/iStock) BARseq reveals that peripheral inputs can alter the identity of cortical neurons during development.
media / MyNorthwest / KIRO Radio
KIRO Radio: Breakthroughs in Synthetic Biology
(Interview starts 11:35 in) Troy McDiarmid from the Seattle Center for Synthetic Biology describes the innovative research underway to create cellular recorders that will track the full life histories of human cells to better understand disease.
media / Puget Sound Business Journal
Puget Sound Business Journal: Seattle biotech research hub launches with big goals for growth, scientific advances
The Seattle Hub for Synthetic Biology is developing technology to monitor genomic changes in cells in real time, in turn showing cells' whole histories and the genetic causes of disease.
media / Inside Precision Medicine
Inside Precision Medicine: How Single-Cell Omics is Revolutionizing Our View Of Neurobiology
(Photo credit: miakievy / Getty Images) The adult human brain is made up of billions of neurons and glial cells. Understanding the diversity of these cells and their distinctive gene-regulatory mechanisms is crucial for determining how the brain works and, in turn, for developing treatments for neurologic disorders
media / GeekWire
GeekWire: Inside the new Seattle Hub for Synthetic Biology, which uses DNA to ‘record biology over time’
(Photo credit: Charlotte Schubert) Researchers opened the doors Monday to the new Seattle Hub for Synthetic Biology, a collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington.
media / The Scientist
The Scientist: A Cell-by-Cell Map of the Entire Mouse Brain
This comprehensive map laid the foundation for the next stage of investigations, such as scaling up efforts to chart nonhuman primates and human brains.
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