stories
news from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
Zapping the right brain cells: The path to improved stimulation
New findings could help scientists develop better ways to treat brain disorders with electrical stimulation.
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A day in the (neuroscience) life: Human cell types
Scientists in this laboratory are exploring the molecular details of human - and other primate - brain cells
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A day in the (neuroscience) life: Electrophysiology
The researchers in this laboratory spend their days eavesdropping on neurons’ electrical chatter
brain science
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A day in the (neuroscience) life: Tissue Processing
The researchers in this lab prepare brain tissue for several other teams at the Allen Institute
brain science
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SciShots: A sneak peek of a new Alzheimer’s disease project
Researchers are in the early stages of investigating the brain cells most vulnerable to this devastating form of dementia
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How do our neurons connect? New study probes the details of human and mouse synapses
‘Multipatch’ technique catalogs more than 1700 connections between neurons in publicly released dataset
brain science
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SciShots: Neurons in crisp, clear detail
Electron microscopy reveals the stunning 3D shapes of mouse visual neurons
brain science
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SciShots: A crown of neurons
Brain-wide neuron tracing of cells in the mouse claustrum, a mysterious structure that’s highly connected to the rest of the brain
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SciShots: A neuron’s love connection
A specialized team of neuroscientists at the Allen Institute spend their days painstakingly tracing neurons’ complex branching structures
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A map of all our brains’ blood vessel cells finds new clues to Alzheimer’s disease
Scientists release the first cell-by-cell atlas of the human blood-brain barrier.
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The Paul G. Allen Frontiers Group announces 23 new Allen Distinguished Investigators
$15.5M in research funding will support cutting-edge projects in mammalian synthetic biology, the neuroscience of under-studied animals, and tiny...
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Fierce Biotech: Allen Institute's cell lines could lead to new drugs for hypertrophic cardiomyopathy
(Photo credit: Fierce Biotech) By helping scientists make generalizations about the disease by unearthing the common denominator between mutations, the cells could ultimately lead to more personalized treatment approaches.
KIRO Radio: Breakthroughs in Synthetic Biology
(Interview starts 11:35 in) Troy McDiarmid from the Seattle Center for Synthetic Biology describes the innovative research underway to create cellular recorders that will track the full life histories of human cells to better understand disease.
Puget Sound Business Journal: Seattle biotech research hub launches with big goals for growth, scientific advances
The Seattle Hub for Synthetic Biology is developing technology to monitor genomic changes in cells in real time, in turn showing cells' whole histories and the genetic causes of disease.
Inside Precision Medicine: How Single-Cell Omics is Revolutionizing Our View Of Neurobiology
(Photo credit: miakievy / Getty Images) The adult human brain is made up of billions of neurons and glial cells. Understanding the diversity of these cells and their distinctive gene-regulatory mechanisms is crucial for determining how the brain works and, in turn, for developing treatments for neurologic disorders
GeekWire: Inside the new Seattle Hub for Synthetic Biology, which uses DNA to ‘record biology over time’
(Photo credit: Charlotte Schubert) Researchers opened the doors Monday to the new Seattle Hub for Synthetic Biology, a collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington.
