stories
news from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
Zapping the right brain cells: The path to improved stimulation
New findings could help scientists develop better ways to treat brain disorders with electrical stimulation.
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A day in the (neuroscience) life: Human cell types
Scientists in this laboratory are exploring the molecular details of human - and other primate - brain cells
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A day in the (neuroscience) life: Electrophysiology
The researchers in this laboratory spend their days eavesdropping on neurons’ electrical chatter
brain science
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A day in the (neuroscience) life: Tissue Processing
The researchers in this lab prepare brain tissue for several other teams at the Allen Institute
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SciShots: A sneak peek of a new Alzheimer’s disease project
Researchers are in the early stages of investigating the brain cells most vulnerable to this devastating form of dementia
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How do our neurons connect? New study probes the details of human and mouse synapses
‘Multipatch’ technique catalogs more than 1700 connections between neurons in publicly released dataset
brain science
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SciShots: Neurons in crisp, clear detail
Electron microscopy reveals the stunning 3D shapes of mouse visual neurons
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SciShots: A crown of neurons
Brain-wide neuron tracing of cells in the mouse claustrum, a mysterious structure that’s highly connected to the rest of the brain
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SciShots: A neuron’s love connection
A specialized team of neuroscientists at the Allen Institute spend their days painstakingly tracing neurons’ complex branching structures
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A map of all our brains’ blood vessel cells finds new clues to Alzheimer’s disease
Scientists release the first cell-by-cell atlas of the human blood-brain barrier.
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The Paul G. Allen Frontiers Group announces 23 new Allen Distinguished Investigators
$15.5M in research funding will support cutting-edge projects in mammalian synthetic biology, the neuroscience of under-studied animals, and tiny...
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Science Friday: 3,000 Types Of Brain Cells Categorized In Massive Brain Cell Atlas
In October 2023, an international group of scientists released an impressively detailed cell atlas of the human brain, published in 21 papers in the journals Science, Science Advances and Science Translational Medicine.
STAT: Allen Institute CEO Rui Costa on mapping the brain and paying early-career scientists decent salaries
Mapping the billions of cells that make up the brain is a task mammoth enough to keep hundreds of researchers across continents busy for years. But it’s just one of several ambitious projects the Allen Institute is helping tackle.
Scientific American: First Atlas of Every Mouse Brain Cell Could Improve Neuro Disease Treatments
Neuroscientists have unveiled their most comprehensive and detailed map of cell types across the entire mouse brain, delivering the latest results of a six-year-long scientific effort in which Seattle’s Allen Institute has played a leading role.
Quanta Magazine: New Cell Atlases Reveal Untold Variety in the Brain and Beyond
(Photo credit: Peter Greenwood for Quanta Magazine.) Recent efforts to map every cell in the human body have researchers floored by unfathomable diversity, with many thousands of subtly different types of cells in the human brain alone.
Seattle Times: Research that brings AI into human cells will soon expand in Seattle
The Seattle Hub for Synthetic Biology, set to open in January, is a result of collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington that aims to build new technologies to record the history of our bodies’ cells.
Yahoo News: Allen Frontiers Group awards $10M to set up research center for neuroimmunology
The neuroimmunology research center will be led by Brian Kim of Mount Sinai and David Artis of Weill Cornell Medicine. They’ll bring together a multidisciplinary team to trace interactions between the nervous system and the immune system that occur at sites distant from the brain.
