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From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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Zapping the right brain cells: The path to improved stimulation

New findings could help scientists develop better ways to treat brain disorders with electrical stimulation.
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news 
New grants to study the aging brain and build better tools to access brain cells
NIH funding will support an atlas of aging mouse brain cell types and a toolkit to light up specific brain cell types
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Data Stories | How a weight loss drug acts on the brain
Scientists at a pharmaceutical company want to know how the drug they developed for weight management affects the brain. Allen Institute resources are...
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A computational challenge to help developmental biology
Q&A with the scientists and organizers behind a new competition to use machine learning to reconstruct an entire animal’s developmental lineage
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Three collaborative studies launch on ‘OpenScope,’ a shared observatory for neuroscience
2019 projects will tackle Alzheimer’s disease, motion detection, and how the brain processes contextual information
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Allen Cell Methods: Cryopreservation of clonal human iPS cell lines in 96-well plates
To ensure researchers have success working with human induced pluripotent stem cell lines from the Allen Cell Catalog, Amanda Haupt, a research...
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How the gut keeps time - and keeps us healthy
New study identifies brain-intestine circadian signals that could underlie health problems related to night shift work and poor sleep
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Highest-Resolution Human Brain 'Parts List' To Date Lays Road Map to Better Treatments for Neurological and Psychiatric Disorders
Crucial differences discovered in human and mice brain cells could explain why many drugs that work in the lab don’t work in us
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This is what it’s like to donate your brain to science
Casey Schorr underwent invasive surgery to quell the epileptic seizures that were taking over his life. Now, a small piece of his brain tissue is...
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Virtual reality is helping neuroscientists better understand the brain
When Elise Shen goes to work, her morning starts much like that of anyone else with a desk job. She greets her coworkers. She fetches a cup of coffee....
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Simulations of life - in health and disease
Across many areas of biology, researchers are turning to virtual simulations to help ask and answer important questions.
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Machine learning toolkit lets biologists navigate their way through a 3D cell
In the world of computer vision, engineers need to build software that can recognize parts of an image or 3D visual field. Think, for example, a...
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These neurons are tied to one of multiple sclerosis’ most dramatic effects: Brain shrinkage
Multiple sclerosis begins with a maddening back and forth.
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media / Nature
🔒 Nature: Method of the Year: EM connectomics
To understand the brain, it matters to precisely map how the brain’s neurons connect.
media / Nature
🔒 Nature: The ‘silent’ brain cells that shape our behaviour, memory and health
A rush of studies from labs in many subfields are revealing just how important astrocytes are in shaping our behavior, mood and memory.
media / Popular Mechanics
🔒 Popular Mechanics: Scientists Are Gifting AI the Final Ingredient for Consciousness—And It Could Trigger the Singularity
A tech company is working on creating “micro-emotions” within AI to see how it effects their behavior, but not everyone buys into the idea.
media / The Scientist
The Scientist: A New Cell Atlas Helps Researchers Navigate the Developing Brain
Researchers collaborating on a BRAIN Initiative project unveiled the most comprehensive map of developing mammalian brains to date.
media / Washington Post
🔒 Washington Post: These people experienced near death. Here’s how it changed their lives.
As many as 17 percent of people have had a near-death experience and these events can permanently affect a person’s life.
media / The Transmitter
The Transmitter: Gene replacement therapy normalizes some traits in SYNGAP1 model mice
The first published virus-based gene therapy for SYNGAP1 deletion yields benefits despite the gene’s long length and complexity.
media / Daily Mail
Daily Mail: Stunning simulation details 10 MILLION neurons across 86 interconnected regions
Scientists have unveiled the most detailed map of the brain ever created with Fugaku, Japan's ultra–fast supercomputer.
media / GeekWire
GeekWire: Scientists create a supercomputer simulation that can reveal how the brain works, neuron by neuron
The simulation could eventually open the way to understanding the mechanisms behind brain disease.
media / GeekWire
GeekWire: Allen Institute taps AWS, Google to spur ‘aha moments’ in neuroscience with new brain research platform
The project aims to unify brain information from dozens of collaborators, species, and samples that span early development to old age.
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