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From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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Zapping the right brain cells: The path to improved stimulation

New findings could help scientists develop better ways to treat brain disorders with electrical stimulation.
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A day in the (neuroscience) life: Human cell types
Scientists in this laboratory are exploring the molecular details of human - and other primate - brain cells
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A day in the (neuroscience) life: Electrophysiology
The researchers in this laboratory spend their days eavesdropping on neurons’ electrical chatter
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A day in the (neuroscience) life: Tissue Processing
The researchers in this lab prepare brain tissue for several other teams at the Allen Institute
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SciShots: A sneak peek of a new Alzheimer’s disease project
Researchers are in the early stages of investigating the brain cells most vulnerable to this devastating form of dementia
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How do our neurons connect? New study probes the details of human and mouse synapses
‘Multipatch’ technique catalogs more than 1700 connections between neurons in publicly released dataset
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SciShots: Neurons in crisp, clear detail
Electron microscopy reveals the stunning 3D shapes of mouse visual neurons
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SciShots: A crown of neurons
Brain-wide neuron tracing of cells in the mouse claustrum, a mysterious structure that’s highly connected to the rest of the brain
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SciShots: A neuron’s love connection
A specialized team of neuroscientists at the Allen Institute spend their days painstakingly tracing neurons’ complex branching structures
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A map of all our brains’ blood vessel cells finds new clues to Alzheimer’s disease
Scientists release the first cell-by-cell atlas of the human blood-brain barrier.
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The Paul G. Allen Frontiers Group announces 23 new Allen Distinguished Investigators
$15.5M in research funding will support cutting-edge projects in mammalian synthetic biology, the neuroscience of under-studied animals, and tiny...
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SciShots: Cellular scaffolding
Computer animation techniques light up cells’ inner workings
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SciShots: A star-shaped human brain cell
Scientists catch a glimpse of a rare kind of human astrocyte
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media / Allen Institute
The Paul G. Allen Frontiers Group Announces New Allen Distinguished Investigators
Collaborative projects funded by the awards will address important questions about neurodegenerative disease, nucleus biology, and protein turnover
media / Seattle Times
Immunology Institute Founded by Paul Allen Shifts Focus to Tackle Coronavirus
Seattle Times
media / NPR
Alzheimer's Researchers Go Back To Basics To Find The Best Way Forward
NPR - Three research institutions in Seattle have joined forces to study how Alzheimer's disease takes root in the brain.
media / Smithsonian Magazine
Researchers Created a 3-D Map of 100 Million Cells in the Mouse Brain
Smithsonian Magazine - Neuroscientists have been using the tool since 2017 to pinpoint where exactly their data are coming from
media / Nature
Science-ing from home
Nature - In the first of two articles about laboratory closures triggered by COVID-19, scientists affected by the shutdowns outline the tools they are using to run their research groups remotely.
media / Associated Press
Epilepsy treatment side effect: New insights about the brain
AP News - Though Genette Hofmann is still using her brain, last month she donated a bit of it — to science.
media / STAT News
Scientists routinely cure brain disorders in mice but not us. A new study helps explain why
STAT - Lab mice endure a lot for science, but there’s often one (temporary) compensation: near-miraculous recovery from diseases that kill people.
media / Seattle Times
What can mice teach Allen Institute researchers about treating brain disorders in humans?
The Seattle Times - Psychiatric drugs meant for humans have been tested on mice for years. The two species’ brains have similar cellular structures.
media / Scientific American
Scientists Start Building a Parts List for the Brain
Scientific American - A new study provides an extraordinary close-up of the menagerie of neural cell types, yielding possible leads for neurological and psychiatric treatments
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