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From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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Zapping the right brain cells: The path to improved stimulation

New findings could help scientists develop better ways to treat brain disorders with electrical stimulation.
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news 
New research to understand how the brain handles optical illusions and makes predictions
3 new projects launch on OpenScope, a shared neuroscience observatory at the Allen Institute
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SciShots: The labyrinthian protein factory of the cell
Graphics software for microscope imagery lights up the endoplasmic reticulum
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SciShots: How the brain plugs leaks
A delicate molecular dance maintains the blood-brain barrier, protecting the brain while allowing transport of necessary resources
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Why is the human brain so difficult to understand? We asked 4 neuroscientists.
Thoughts, memories, sensations - why are we still in the dark about how they work?
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SciShots: Gentle imaging for delicate cells
Examining fine cellular details for longer time periods
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SciShots: Modeling for the masses
New tool helps scientists see how E. coli finds its center
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Online simulations offer scientists new views inside cells
Simularium Viewer provides interactive visual outputs of computational, biological models
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SciShots: Rare kraken cell line released
Illuminating structures in Magnumlolligo glacies cells with unprecedented detail
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SciShots: One happy cell (nucleus)
Explorations of the nuclear envelope, the thin membrane surrounding a cell’s chromosomes, reveal unexpected wrinkles
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A day in the (neuroscience) life: OpenScope
Scientists on the OpenScope team help share the Allen Institute’s ‘observatory of the mind’ with the larger scientific community
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A day in the (neuroscience) life: Electron microscopy
Researchers on the EM team are viewing the brain in unprecedented detail
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Science in Sixty | Luke Campagnola
When Luke Campagnola isn't investigating the complexities of mammalian brain circuitry, he's spending time with family and practicing parkour.
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media / The Transmitter
The Transmitter: Split gene therapy delivers promise in mice modeling Dravet syndrome
A potential new gene therapy for Dravet syndrome increases survival and prevents seizures in mice, a new study shows.
media / Associated Press
Associated Press: Scientists map part of a mouse’s brain that’s so complex it looks like a galaxy
Thanks to a mouse watching clips from “The Matrix,” scientists have created the largest functional map of a brain to date.
media / New York Times
New York Times: An Advance in Brain Research That Was Once Considered Impossible
Scientists achieved “a milestone” by charting the activity and structure of 200,000 cells in a mouse brain and their 523 million connections.
media / The Transmitter
The Transmitter: Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain
A cubic millimeter of brain tissue reveals in stunning detail the role of inhibitory interneurons in brain structure and function.
media / Brotman Baty Institute
Brotman Baty Institute: Promising Young Scientist: A Researcher Finds ‘Perfect Match for My Professional Interests’ at Seattle Hub
As a teenager, Hina Iftikhar set her sights on practicing medicine in her home country of Pakistan. But her father, a physician, was convinced she could “do much more interesting things in life than become a doctor.”
media / GEN (Genetic Engineering News)
Genetic Engineering & Biotechnology News: Gene Therapy Tested in Mice Offers New Hope for People with Dravet Syndrome
Scientists from the Allen Institute and Seattle Children’s Research Institute have announced a breakthrough in the development of gene replacement therapies for Dravet syndrome.
media / KXLY
KXLY: Groundbreaking gene therapy research in Washington could lead to treat children living with severe epilepsy
Scientists at the Allen Institute have made a major breakthrough in research for people living with Dravet Syndrome.
media / Fox 13 Seattle
Fox 13 Seattle: Breakthrough gene therapy in Seattle offers hope for children with epilepsy
Scientists are working on a promising gene therapy that could offer a life-saving treatment for children suffering from this severe form of epilepsy.
media / Brotman Baty Institute
Brotman Baty Institute: Washington Research Foundation Awards $10M to Seattle Hub to Advance Cell and Genome Technologies
Five-year grant, one of the largest in the foundation's history, will support groundbreaking work by Brotman Baty Institute and the Allen Institute.
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