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From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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Zapping the right brain cells: The path to improved stimulation

New findings could help scientists develop better ways to treat brain disorders with electrical stimulation.
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news 
New research to understand how the brain handles optical illusions and makes predictions
3 new projects launch on OpenScope, a shared neuroscience observatory at the Allen Institute
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SciShots: The labyrinthian protein factory of the cell
Graphics software for microscope imagery lights up the endoplasmic reticulum
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SciShots: How the brain plugs leaks
A delicate molecular dance maintains the blood-brain barrier, protecting the brain while allowing transport of necessary resources
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Why is the human brain so difficult to understand? We asked 4 neuroscientists.
Thoughts, memories, sensations - why are we still in the dark about how they work?
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SciShots: Gentle imaging for delicate cells
Examining fine cellular details for longer time periods
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SciShots: Modeling for the masses
New tool helps scientists see how E. coli finds its center
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Online simulations offer scientists new views inside cells
Simularium Viewer provides interactive visual outputs of computational, biological models
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SciShots: Rare kraken cell line released
Illuminating structures in Magnumlolligo glacies cells with unprecedented detail
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SciShots: One happy cell (nucleus)
Explorations of the nuclear envelope, the thin membrane surrounding a cell’s chromosomes, reveal unexpected wrinkles
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A day in the (neuroscience) life: OpenScope
Scientists on the OpenScope team help share the Allen Institute’s ‘observatory of the mind’ with the larger scientific community
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A day in the (neuroscience) life: Electron microscopy
Researchers on the EM team are viewing the brain in unprecedented detail
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Science in Sixty | Luke Campagnola
When Luke Campagnola isn't investigating the complexities of mammalian brain circuitry, he's spending time with family and practicing parkour.
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media / CBC
CBC Radio: Key players in brain aging: research identifies what's driving age-related changes on a cellular level
How much science is there to support "fountain of youth" marketing claims? Our science columnist Torah Kachur looked into it.
media / Yahoo News
Yahoo News: New discoveries from Seattle scientists could help manage brain's aging process
A new year marks new research on the health and well-being. Scientists ssay new discoveries could help unlock ways to keep the mind sharper, longer.
media / KUOW
KUOW: How brain-mapping research by Seattle scientists could help prevent Alzheimer's
New research may help doctors and drug companies target specific brain cells to help people keep their minds sharp as they age.
media / Fox News
Fox News: Health Aging ‘hotspot’ found in brain, researchers say: ‘Major changes’
The brain plays a big part in the aging process, and scientists think they’ve pinpointed the specific cells that control it.
media / GeekWire
Tech Moves: Allen Institute names new VP
Julie Harris has been appointed vice president of The Paul G. Allen Frontiers Group at the Seattle-based Allen Institute.
media / The Scientist
Charting the Human Immune Health Atlas
Every individual’s immune system is distinct and changes over time, affecting their health and disease response. Recently, researchers mapped human immune cells to explore what defines a healthy immune system across different ages.
media / The Transmitter
The Transmitter: Expanding set of viral tools targets almost any brain cell type
Harmless viruses that encase short noncoding DNA elements called enhancers enable cell-type-specific gene delivery across the central nervous system in rodents and primates.
media / NPR
NPR: Timeline shows what happens to different brain cells as Alzheimer’s progresses
An analysis of brains at various stages of Alzheimer's found that neurons called inhibitory neurons are the first to be affected by the disease.
media / Fox News
Fox News: New Alzheimer’s research reveals ‘quiet’ phase of the disease, before symptoms appear
Researchers led by the Allen Institute for Brain Science in Seattle and University of Washington Medicine have identified cellular changes in the brains of people with the disease — and a timeline of when they occur.
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