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From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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Zapping the right brain cells: The path to improved stimulation

New findings could help scientists develop better ways to treat brain disorders with electrical stimulation.
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news 
New research to understand how the brain handles optical illusions and makes predictions
3 new projects launch on OpenScope, a shared neuroscience observatory at the Allen Institute
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SciShots: The labyrinthian protein factory of the cell
Graphics software for microscope imagery lights up the endoplasmic reticulum
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SciShots: How the brain plugs leaks
A delicate molecular dance maintains the blood-brain barrier, protecting the brain while allowing transport of necessary resources
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Why is the human brain so difficult to understand? We asked 4 neuroscientists.
Thoughts, memories, sensations - why are we still in the dark about how they work?
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SciShots: Gentle imaging for delicate cells
Examining fine cellular details for longer time periods
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SciShots: Modeling for the masses
New tool helps scientists see how E. coli finds its center
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Online simulations offer scientists new views inside cells
Simularium Viewer provides interactive visual outputs of computational, biological models
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SciShots: Rare kraken cell line released
Illuminating structures in Magnumlolligo glacies cells with unprecedented detail
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SciShots: One happy cell (nucleus)
Explorations of the nuclear envelope, the thin membrane surrounding a cell’s chromosomes, reveal unexpected wrinkles
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A day in the (neuroscience) life: OpenScope
Scientists on the OpenScope team help share the Allen Institute’s ‘observatory of the mind’ with the larger scientific community
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A day in the (neuroscience) life: Electron microscopy
Researchers on the EM team are viewing the brain in unprecedented detail
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Science in Sixty | Luke Campagnola
When Luke Campagnola isn't investigating the complexities of mammalian brain circuitry, he's spending time with family and practicing parkour.
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media / Nature
🔒 Nature: Method of the Year: EM connectomics
To understand the brain, it matters to precisely map how the brain’s neurons connect.
media / Nature
🔒 Nature: The ‘silent’ brain cells that shape our behaviour, memory and health
A rush of studies from labs in many subfields are revealing just how important astrocytes are in shaping our behavior, mood and memory.
media / Popular Mechanics
🔒 Popular Mechanics: Scientists Are Gifting AI the Final Ingredient for Consciousness—And It Could Trigger the Singularity
A tech company is working on creating “micro-emotions” within AI to see how it effects their behavior, but not everyone buys into the idea.
media / The Scientist
The Scientist: A New Cell Atlas Helps Researchers Navigate the Developing Brain
Researchers collaborating on a BRAIN Initiative project unveiled the most comprehensive map of developing mammalian brains to date.
media / Washington Post
🔒 Washington Post: These people experienced near death. Here’s how it changed their lives.
As many as 17 percent of people have had a near-death experience and these events can permanently affect a person’s life.
media / The Transmitter
The Transmitter: Gene replacement therapy normalizes some traits in SYNGAP1 model mice
The first published virus-based gene therapy for SYNGAP1 deletion yields benefits despite the gene’s long length and complexity.
media / Daily Mail
Daily Mail: Stunning simulation details 10 MILLION neurons across 86 interconnected regions
Scientists have unveiled the most detailed map of the brain ever created with Fugaku, Japan's ultra–fast supercomputer.
media / GeekWire
GeekWire: Scientists create a supercomputer simulation that can reveal how the brain works, neuron by neuron
The simulation could eventually open the way to understanding the mechanisms behind brain disease.
media / GeekWire
GeekWire: Allen Institute taps AWS, Google to spur ‘aha moments’ in neuroscience with new brain research platform
The project aims to unify brain information from dozens of collaborators, species, and samples that span early development to old age.
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