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From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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Zapping the right brain cells: The path to improved stimulation

New findings could help scientists develop better ways to treat brain disorders with electrical stimulation.
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New research to understand how the brain handles optical illusions and makes predictions
3 new projects launch on OpenScope, a shared neuroscience observatory at the Allen Institute
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SciShots: The labyrinthian protein factory of the cell
Graphics software for microscope imagery lights up the endoplasmic reticulum
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SciShots: How the brain plugs leaks
A delicate molecular dance maintains the blood-brain barrier, protecting the brain while allowing transport of necessary resources
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Why is the human brain so difficult to understand? We asked 4 neuroscientists.
Thoughts, memories, sensations - why are we still in the dark about how they work?
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SciShots: Gentle imaging for delicate cells
Examining fine cellular details for longer time periods
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SciShots: Modeling for the masses
New tool helps scientists see how E. coli finds its center
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Online simulations offer scientists new views inside cells
Simularium Viewer provides interactive visual outputs of computational, biological models
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SciShots: Rare kraken cell line released
Illuminating structures in Magnumlolligo glacies cells with unprecedented detail
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SciShots: One happy cell (nucleus)
Explorations of the nuclear envelope, the thin membrane surrounding a cell’s chromosomes, reveal unexpected wrinkles
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A day in the (neuroscience) life: OpenScope
Scientists on the OpenScope team help share the Allen Institute’s ‘observatory of the mind’ with the larger scientific community
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A day in the (neuroscience) life: Electron microscopy
Researchers on the EM team are viewing the brain in unprecedented detail
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Science in Sixty | Luke Campagnola
When Luke Campagnola isn't investigating the complexities of mammalian brain circuitry, he's spending time with family and practicing parkour.
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media / Allen Institute
The Paul G. Allen Frontiers Group Announces New Allen Distinguished Investigators
Collaborative projects funded by the awards will address important questions about neurodegenerative disease, nucleus biology, and protein turnover
media / Seattle Times
Immunology Institute Founded by Paul Allen Shifts Focus to Tackle Coronavirus
Seattle Times
media / NPR
Alzheimer's Researchers Go Back To Basics To Find The Best Way Forward
NPR - Three research institutions in Seattle have joined forces to study how Alzheimer's disease takes root in the brain.
media / Smithsonian Magazine
Researchers Created a 3-D Map of 100 Million Cells in the Mouse Brain
Smithsonian Magazine - Neuroscientists have been using the tool since 2017 to pinpoint where exactly their data are coming from
media / Nature
Science-ing from home
Nature - In the first of two articles about laboratory closures triggered by COVID-19, scientists affected by the shutdowns outline the tools they are using to run their research groups remotely.
media / Associated Press
Epilepsy treatment side effect: New insights about the brain
AP News - Though Genette Hofmann is still using her brain, last month she donated a bit of it — to science.
media / STAT News
Scientists routinely cure brain disorders in mice but not us. A new study helps explain why
STAT - Lab mice endure a lot for science, but there’s often one (temporary) compensation: near-miraculous recovery from diseases that kill people.
media / Seattle Times
What can mice teach Allen Institute researchers about treating brain disorders in humans?
The Seattle Times - Psychiatric drugs meant for humans have been tested on mice for years. The two species’ brains have similar cellular structures.
media / Scientific American
Scientists Start Building a Parts List for the Brain
Scientific American - A new study provides an extraordinary close-up of the menagerie of neural cell types, yielding possible leads for neurological and psychiatric treatments
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