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From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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Zapping the right brain cells: The path to improved stimulation

New findings could help scientists develop better ways to treat brain disorders with electrical stimulation.
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New research to understand how the brain handles optical illusions and makes predictions
3 new projects launch on OpenScope, a shared neuroscience observatory at the Allen Institute
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SciShots: The labyrinthian protein factory of the cell
Graphics software for microscope imagery lights up the endoplasmic reticulum
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SciShots: How the brain plugs leaks
A delicate molecular dance maintains the blood-brain barrier, protecting the brain while allowing transport of necessary resources
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Why is the human brain so difficult to understand? We asked 4 neuroscientists.
Thoughts, memories, sensations - why are we still in the dark about how they work?
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SciShots: Gentle imaging for delicate cells
Examining fine cellular details for longer time periods
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SciShots: Modeling for the masses
New tool helps scientists see how E. coli finds its center
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Online simulations offer scientists new views inside cells
Simularium Viewer provides interactive visual outputs of computational, biological models
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SciShots: Rare kraken cell line released
Illuminating structures in Magnumlolligo glacies cells with unprecedented detail
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SciShots: One happy cell (nucleus)
Explorations of the nuclear envelope, the thin membrane surrounding a cell’s chromosomes, reveal unexpected wrinkles
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A day in the (neuroscience) life: OpenScope
Scientists on the OpenScope team help share the Allen Institute’s ‘observatory of the mind’ with the larger scientific community
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A day in the (neuroscience) life: Electron microscopy
Researchers on the EM team are viewing the brain in unprecedented detail
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Science in Sixty | Luke Campagnola
When Luke Campagnola isn't investigating the complexities of mammalian brain circuitry, he's spending time with family and practicing parkour.
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media / Yahoo News
Yahoo News: A new batch of 'brain atlases' shows how brain cells change from embryo to maturity
The field could soon show when problems like dementia emerge.
media / Fox 13 Seattle
Fox 13 Seattle: Why flu shots work differently in older adults
It is flu season and there is some new insight into why vaccines may work less effectively in older adults.
media / Science
Science: Can AI capture the mind-boggling complexity of a human cell?
Researchers have started to build systems of equations meant to simulate some of the cell’s workings.
media / KOMO News
KOMO: Allen Institute scientists crack code on why flu shots work differently in older adults
Scientists at the Allen Institute are learning more about why vaccines can trigger a weaker response in some older adults.
media / The Scientist
The Scientist: Aging Reprograms T Cell Behavior, Weakening Vaccine Responses
By profiling over 16 million immune cells after flu vaccination, scientists discovered that memory T cell function changes with age.
media / The Scientist
The Scientist: A Neural Network Maps the Mouse Brain in Unprecedented Detail
Using spatial transcriptomics and AI, researchers redefined the mouse brain’s geography, uncovering hundreds of new subregions.
media / GeekWire
GeekWire: Tech Moves: Allen Institute gets new exec
Award-winning immunologist ​​Susan Kaech is the new executive vice president of the Allen Institute’s Immunology Moonshot.
media / FOX Chicago
FOX Chicago: Can you really trust your gut? The science behind our 'sixth sense'
This NIH-supported project aims to uncover the body’s true “sixth sense” — the subconscious communication between the brain and organs.
media / Time
Time: Why AI Companies Are Racing to Build a Virtual Human Cell
Cells are so complex, which is why some researchers are using AI to take new steps towards the goal of a “virtual cell.”
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