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From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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Zapping the right brain cells: The path to improved stimulation

New findings could help scientists develop better ways to treat brain disorders with electrical stimulation.
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An ultra detailed map of the brain region that controls movement, from mice to monkeys to humans
Hundreds of neuroscientists built a ‘parts list’ of the motor cortex, laying groundwork to map the whole brain and better understand brain disease...
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These rare human neurons generate electrical signals in two different cellular parts
With brain tissue samples donated by surgery patients come detailed descriptions of certain rare types of human cells - including new findings about...
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Q&A with the Allen Institute for Immunology’s first employee
Ernie Coffey started his career in science with a bang. It was 1997 and he landed a job at one of the institutes participating in the sequencing of...
immunology
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Sped-up evolution may have molded the human brain by slowing neuron growth
Quickly evolving stretches of DNA unique to humans are important for brain development, a new study finds
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Brain scientists unveil wiring diagram containing 200,000 cells and nearly half billion connections in tiny piece of a mouse's brain
Detailed map captures 3D shapes of neurons and their synapses in stunning detail and is open to community for neuroscience and machine learning...
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To understand human cells, scientists look beyond genes
Deep dive into detailed images of human heart cells uncovers a disconnect between gene expression and cell structure
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Science in Sixty | Shannon Reynolds
Figuring out how to transport live brain tissue from the operating room to the lab is challenging to say the least. In our latest Science in Sixty,...
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Study maps all the types of neurons across two major structures of the mouse brain
Cell-type parts list of the mouse neocortex and the hippocampal formation yields new information about how the mammalian brain evolved and develops
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Science in Sixty | Brian Lee
Brian Lee, Ph.D., barely graduated high school. Now he has his Ph.D., and is running a lab at the Allen Institute for Brain Science.
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New technique explores the ins and outs of our immune cells
Method that captures 3 different characteristics of individual human cells at once can shed light on aging and disease.
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Allen Institute and BioMarin team up to develop gene therapies for rare brain diseases.
The collaboration leverages technologies intended to target gene expression to specific cells within the central nervous system
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Science in Sixty | Ru Gunawardane
Ru Gunawardane, Ph.D., is the Executive Director of the Allen Institute for Cell Science, where she leads a team of scientists, engineers, artists and other experts, all working together to understand how our cells function.
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media / Yahoo News
Yahoo News: A new batch of 'brain atlases' shows how brain cells change from embryo to maturity
The field could soon show when problems like dementia emerge.
media / Fox 13 Seattle
Fox 13 Seattle: Why flu shots work differently in older adults
It is flu season and there is some new insight into why vaccines may work less effectively in older adults.
media / Science
Science: Can AI capture the mind-boggling complexity of a human cell?
Researchers have started to build systems of equations meant to simulate some of the cell’s workings.
media / KOMO News
KOMO: Allen Institute scientists crack code on why flu shots work differently in older adults
Scientists at the Allen Institute are learning more about why vaccines can trigger a weaker response in some older adults.
media / The Scientist
The Scientist: Aging Reprograms T Cell Behavior, Weakening Vaccine Responses
By profiling over 16 million immune cells after flu vaccination, scientists discovered that memory T cell function changes with age.
media / The Scientist
The Scientist: A Neural Network Maps the Mouse Brain in Unprecedented Detail
Using spatial transcriptomics and AI, researchers redefined the mouse brain’s geography, uncovering hundreds of new subregions.
media / GeekWire
GeekWire: Tech Moves: Allen Institute gets new exec
Award-winning immunologist ​​Susan Kaech is the new executive vice president of the Allen Institute’s Immunology Moonshot.
media / FOX Chicago
FOX Chicago: Can you really trust your gut? The science behind our 'sixth sense'
This NIH-supported project aims to uncover the body’s true “sixth sense” — the subconscious communication between the brain and organs.
media / Time
Time: Why AI Companies Are Racing to Build a Virtual Human Cell
Cells are so complex, which is why some researchers are using AI to take new steps towards the goal of a “virtual cell.”
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